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Which of the following represents the largest fluid compartment?


A) Intracellular fluid
B) Extracellular fluid
C) Interstitial fluid
D) Blood plasma
E) Lymph

F) A) and D)
G) B) and E)

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Which of the following is not a function of the carbonic acid/bicarbonate system?


A) Regulation of the pH of the intracellular environment
B) Regulating pH changes of the blood during exercise
C) Regulation of blood pH during elevated fat matabolism
D) Regulation of blood pH in coordination with the respiratory system
E) Regulation of blood pH in coordination with the kidneys

F) B) and D)
G) C) and D)

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In renal compensation of acidosis,


A) H+ secretion decreases; bicarbonate excretion increases.
B) H+ secretion decreases; bicarbonate reabsorption increases.
C) H+ secretion increases; bicarbonate reabsorption increases.
D) H+ secretion increases; bicarbonate excretion increases.
E) H+ secretion decreases; bicarbonate excretion decreases.

F) A) and E)
G) A) and B)

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Azetazolamide (Diamox) is a diuretic.It functions by blocking the activity of carbonic anhydrase inside kidney tubule cells.This slows the formation of carbonic acid.By slowing the formation of hydrogen ions in the cells of the tubule,sodium reabsorption is also slowed.This results in the diuretic effect.Select from the following list the possible side-effects of Azetazolamide. (1) acidosis (2) reduced movement of bicarbonate ion into the plasma (3) an alkaline urine is produced (4) respiration increases


A) 1,4
B) 2,3
C) 1,2,3
D) 2,3,4
E) 1,2,3,4

F) C) and D)
G) B) and C)

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The predominant extracellular cation is


A) bicarbonate.
B) sodium.
C) chloride.
D) potassium.
E) hydrogen ion.

F) A) and B)
G) A) and C)

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Extracellular fluid has a


A) higher protein content than intracellular fluid.
B) higher potassium content than intracellular fluid.
C) higher sodium content than intracellular fluid.
D) higher magnesium content than intracellular fluid
E) higher number of large organic molecules than intracellular fluid.

F) A) and D)
G) A) and E)

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When aldosterone is absent,sodium reabsorption in the nephron is


A) greatly increased.
B) greatly decreased.
C) unchanged.

D) A) and B)
E) None of the above

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A person working in the hot sun loses the greatest amount of water from the


A) lungs.
B) urine.
C) mouth.
D) skin.
E) GI tract.

F) A) and E)
G) A) and C)

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Chemicals that function to minimize changes in the pH of body fluids are called


A) buffers.
B) inhibitors.
C) accelerators.
D) activators.
E) stabilizers.

F) A) and D)
G) C) and D)

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You've been working outside in the hot sun and are dripping wet with sweat.Your fluid intake has been minimal as you have been too busy to stop and get a drink.You would expect


A) your blood osmolality to be low.
B) an increase in the production of urine.
C) aldosterone levels to decrease.
D) ADH levels to increase.
E) ADH levels to decrease.

F) C) and D)
G) C) and E)

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The most common cause of hyperkalemia is


A) vomiting.
B) increased dietary intake.
C) increased urinary output.
D) cellular injury or death.
E) diarrhea.

F) C) and D)
G) All of the above

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Which of the following statements concerning potassium ions is false?


A) An increase in the extracellular potassium ion concentration leads to depolarization.
B) Potassium ions are secreted into the nephron by the distal convoluted tubule.
C) When aldosterone levels are high,potassium secretion is low.
D) Aldosterone secretion is stimulated by high blood levels of potassium ions.
E) None of these choices is false.

F) B) and D)
G) All of the above

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Respiratory alkalosis can occur as a result of


A) asphyxia.
B) asthma.
C) severe emphysema.
D) hyperventilation.
E) hypoventilation.

F) B) and E)
G) C) and D)

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If the hydrogen ion concentration in the blood increases,bicarbonate ions act as buffers by


A) removing excess hydrogen ions from the plasma.
B) releasing hydrogen ions into the plasma.
C) dissociating into H+ and CO3-.
D) combining with chloride ions.
E) combining with hemoglobin.

F) B) and E)
G) C) and E)

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Potassium levels in the body are regulated by


A) ADH.
B) PTH.
C) calcitonin.
D) aldosterone.
E) insulin.

F) C) and E)
G) C) and D)

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Which of the following is NOT a principle sensor for thirst regulation?


A) osmoreceptors in the hypothalamus
B) arterial baroreceptors
C) juxtaglomerular apparatus
D) mouth mucosa

E) A) and D)
F) B) and C)

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Atrial natriuretic hormone increases


A) urine volume.
B) ADH secretion.
C) aldosterone secretion.
D) the reabsorption of sodium ions.
E) blood volume.

F) A) and B)
G) B) and D)

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Prolonged vomiting of stomach contents will result in


A) metabolic acidosis.
B) metabolic alkalosis.
C) respiratory acidosis.
D) respiratory alkalosis.
E) None of these choices is correct.

F) A) and B)
G) A) and C)

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Under normal conditions,most water loss from the body is through the


A) skin.
B) kidneys.
C) lungs.
D) GI tract.
E) sweat.

F) A) and E)
G) None of the above

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An increase in the osmolarity of the extracellular fluid will trigger a(n) ___________ in the secretion of ADH and a(n) ____________ in thirst.


A) increase; increase
B) increase; decrease
C) decrease; decrease
D) decrease; increase

E) A) and C)
F) B) and D)

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