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When the substrate is bound to the enzyme,the shape of the enzyme may change slightly,leading to


A) an induced fit
B) a great range of possible catalytic activities
C) a greater supply of activation energy
D) more permanent binding through intimate total contact
E) more possible products of the reaction

F) B) and E)
G) A) and B)

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The Law of Thermodynamics that states that energy cannot be created or destroyed is:


A) The First Law of Thermodynamics
B) The Second Law of Thermodynamics
C) The Third Law of Thermodynamics
D) The Fourth Law of Thermodynamics

E) B) and D)
F) A) and B)

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A

You return home to find that your baby brother has scattered his toy trains and trucks all over the floor of your room.As you begin to pick up the toys and put them away,you realize that even though he is just a baby,he has clearly mastered:


A) the first law of thermodynamics.
B) the second law of thermodynamics.
C) potential energy.
D) free energy.

E) All of the above
F) A) and D)

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It is summer,and you are excited about going to your local amusement park,and specifically about riding the new roller coaster that was just built.You imagine waiting at the top of the stairs for the roller coaster to pull into the station,climbing into the car,strapping yourself into the seatbelt,and pulling down the harness.You can imagine the cars slowly chugging up to the top of the first hill,coming down on the other side,and the excitement you expect to feel as you go along for the ride.Of all of the things that you have imagined,which is an example of potential energy?


A) Waiting at the top of the stairs for the roller coaster to pull into the station
B) Climbing into the car
C) Pulling down the harness
D) The roller coaster car going up the first hill

E) B) and D)
F) None of the above

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For a particular chemical reaction,the enthalpy of the reactants is -400 kJ.The enthalpy of the products is -390 kJ.The entropy of the reactants is 0.2 kJ/K.The entropy of the products is 0.3 kJ/K.The temperature of the reaction is 25 degrees Celsius.What can you conclude about this reaction?


A) It is exergonic
B) It is endergonic
C) it is a redox reaction
D) It is being catalyzed by an enzyme

E) None of the above
F) All of the above

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Why do we have storage macromolecules,such as fats,in our bodies?


A) We can break down these macromolecules to provide energy for the endergonic reactions in our bodies.
B) Human cells can directly capture the energy of sunlight through photosynthesis and store it as macromolecules such as fats.
C) Macromolecules,such as fats,are a convenient way to store kinetic energy.
D) Breaking down macromolecules,such as fats,is an endergonic process.

E) None of the above
F) B) and D)

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Glycolysis is a metabolic process that is conducted by nearly all cells.However,in addition to glycolysis,some cells also make use of another metabolic process called the Krebs cycle.What does this tell you about the evolution of these processes?


A) As a metabolic process,glycolysis likely evolved prior to the Krebs cycle
B) As a metabolic process,the Krebs cycle likely evolved prior to glycolysis
C) Both the Krebs cycle and glycolysis likely evolved at the same time

D) A) and B)
E) A) and C)

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The term oxidation is derived from the name of the element oxygen.This is reasonable,because oxygen


A) attracts electrons very strongly.
B) can be oxidized by accepting electrons.
C) contains more electrons than are needed.
D) passes electrons to many other types of molecules.

E) A) and B)
F) None of the above

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You eat a bowl of beans as part of your dinner.As you digest the beans,the proteins that are present get broken down to their component amino acids.As your body destroys the macromolecules that were present in the beans,is the energy present in those molecules destroyed?


A) Yes.By breaking down these macromolecules,some of the energy they contained is destroyed.
B) No.While the vast majority of the energy contained in these macromolecules is converted to heat,it is not actually destroyed.
C) No.The energy contained within these macromolecules is converted into other forms of chemical energy and kinetic energy,though some is lost as heat.
D) No.Breaking down molecules does not lead to the release of energy.

E) B) and C)
F) A) and D)

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The synthesis of sugar molecules through the process of photosynthesis requires energy absorbed from sunlight.Bearing this in mind,what kind of reaction is photosynthesis?


A) exergonic
B) endergonic
C) catabolic
D) feedback

E) C) and D)
F) B) and D)

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Phosphofructokinase (PFK) is an enzyme that converts fructose 6-phosphate to fructose 1,6-bisphosphate,by adding a phosphate group.This is the first committed step of the metabolic pathway of glycolysis,and thus it is very tightly regulated.AMP binds to PFK at a site distinct from the binding site for fructose 6-phosphate,and stimulates the formation of fructose 1,6-bisphosphate.ATP binds to PFK at a site distinct from the binding site for fructose 6-phosphate,and inhibits the formation of fructose 1,6-bisphosphate.There are other regulators of this enzyme as well.What is the role of AMP in this example?


A) Competitive inhibitor
B) Noncompetitive inhibitor
C) Allosteric inhibitor
D) Allosteric activator
E) Catalyst

F) A) and E)
G) A) and B)

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When an atom or molecule gains one or more electrons,it is said to be:


A) energized.
B) oxidized.
C) polarized.
D) reduced.

E) A) and D)
F) None of the above

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Many metabolic pathways are ultimately concerned with ATP; either with the generation of ATP,or with the requirement of ATP for that pathway to function.Why is ATP so important to metabolism?


A) Hydrolysis of ATP is used to drive exergonic reactions
B) Hydrolysis of the bond between adenine and ribose in ATP is commonly used to release energy that can be used to drive other cellular reactions
C) The phosphate groups of ATP are held together by unstable bonds that can be broken to release energy
D) ATP is a protein that serves as the energy currency of cells

E) A) and B)
F) C) and D)

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C

The ultimate source of energy for humans comes from what source?


A) The sun
B) Plants
C) Water
D) Air
E) Animals

F) A) and D)
G) A) and C)

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Glucose is converted into glucose 6-phosphate by hexokinase.Glucose 6-phosphate then serves as the substrate for the enzyme phosphoglucose isomerase,which converts this reactant into fructose 6-phosphate.Fructose 6-phosphate serves as the substrate for phosphofructokinase,which converts fructose 6-phosphate into fructose 1,6-bisphosphate.Based on the information provided,this is an example of what?


A) Feedback inhibition
B) Allosteric regulation
C) A metabolic pathway
D) Enzyme inhibition

E) None of the above
F) B) and C)

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Metabolic reactions fall under two general categories: anabolic and catabolic.What type of chemical reactions are these two classes of metabolic reactions?


A) Anabolic reactions are exergonic reactions,whereas catabolic reactions are endergonic.
B) Both anabolic and catabolic reactions are exergonic.
C) Both anabolic and catabolic reactions are endergonic.
D) Anabolic reactions are endergonic reactions,whereas catabolic reactions are exergonic.

E) A) and B)
F) A) and C)

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A particular reaction has a negative delta G.However,this reaction takes many years to proceed in the absence of enzyme.Why is this the case?


A) This reaction does not obey the second law of thermodynamics
B) This reaction does not proceed spontaneously
C) The initial free energy of the reactants is much less than the final free energy of the products
D) A certain amount of activation energy is required for the reaction to proceed

E) A) and D)
F) A) and C)

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A calorie is the commonly used unit of chemical energy.It is also the unit of


A) light.
B) magnetism.
C) sound.
D) heat.
E) radioactivity.

F) A) and B)
G) C) and E)

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D

RNA molecules that also act as enzymes are given the name


A) ribozymes
B) cofactors
C) coenzymes
D) allosteric enzymes

E) B) and C)
F) C) and D)

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The organic nonprotein components that aid in enzyme functioning are called


A) reactants.
B) chaperones.
C) coenzymes.
D) substrates.
E) products.

F) None of the above
G) A) and B)

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