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Where are the inspiratory and expiratory centers in the brain found?


A) Broca's area
B) Neurons in the cerebellum
C) Pons
D) No such centers exist

E) B) and C)
F) A) and B)

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What is the response of a patient with chronic hypercapnia to a sudden acute rise in carbon dioxide?


A) In almost all of these patients, there will be no response.
B) The patient's drive to breathe will be increased.
C) This will further depress his or her respiratory centers.
D) This will induce apnea and sudden death.

E) None of the above
F) B) and C)

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B

The pneumotaxic center controls which of the following?


A) Response to changes in blood pH and PCO2
B) Rhythm of the full breathing cycle
C) When inspiration switches off (the inspiratory time)
D) When inspiration switches on (the expiratory time)

E) A) and C)
F) B) and C)

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Both anemia and carbon monoxide (CO) poisoning can cause severe hypoxia, yet neither condition results in a major stimulation of breathing. Why is this so?


A) The peripheral chemoreceptors do not respond to low O2 content.
B) Anemia and CO poisoning depresses the peripheral chemoreceptors.
C) Anemia and CO poisoning depresses the central chemoreceptors.
D) Anemia and CO cause stagnant hypoxia, not hypoxemia.

E) A) and B)
F) A) and C)

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Biot's respiration is most frequently observed in patients with which of the following?


A) Congestive heart failure
B) Increased intracranial pressure
C) Metabolic acidosis
D) Peripheral nerve disorders

E) A) and C)
F) B) and C)

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What is the effect when the deflation reflex is stimulated?


A) A strong inspiratory effort
B) Expiration is initiated
C) Cuts off all inspiratory signals
D) Stimulates the termination of expiration

E) A) and D)
F) B) and C)

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Stimulation of the irritant receptors in the lung can result in which of the following? 1) Bronchoconstriction 2) Coughing 3) Narrowing of the glottis


A) 1 only
B) 1 and 3 only
C) 1, 2, and 3
D) 1 and 2 only

E) A) and B)
F) A) and C)

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Which of the following can be stimulated by pulmonary J receptors? 1) Edema 2) Inflammatory processes 3) Pulmonary vascular congestion


A) 1 and 2 only
B) 1 only
C) 1 and 3 only
D) 1, 2, and 3

E) All of the above
F) C) and D)

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Which of the following can cause laryngospasm and bradycardia through a vagovagal reflex? 1) Bronchoscopy 2) Endotracheal intubation 3) Tracheal suctioning


A) 1 only
B) 1 and 3 only
C) 1, 2, and 3
D) 1 and 2 only

E) A) and B)
F) A) and C)

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Which statement(s) describe aspects of the Hering-Breuer reflex? 1) It affects the rate and depth of breathing during exercise. 2) It is only activated at large tidal volumes in normal adults. 3) Its impulses travel via the vagus nerve to the dorsal respiratory groups (DRGs) . 4) Its receptors are located in the large and small airways.


A) 1 only
B) 1 and 2 only
C) 2, 3, and 4 only
D) 1, 2, 3, and 4

E) A) and B)
F) B) and D)

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Which of the following causes hypoxic stimulation of the carotid bodies? 1) Large decrease in arterial PO2 2) Large decrease in O2 content 3) CO poisoning


A) 1 only
B) 1 and 2 only
C) 1, 2, and 3
D) 1 and 3 only

E) None of the above
F) All of the above

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Which respond more rapidly to high levels of CO2?


A) Aortic chemoreceptors
B) Carotid chemoreceptors
C) Central chemoreceptors
D) Ventral respiratory centers

E) B) and D)
F) A) and D)

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B

In the face of chronically elevated levels of CO2, what happens to the response mediated by the central chemoreceptors?


A) It is accentuated or increased.
B) It is muted or decreased.
C) There is no change in the response.
D) There is no way to predict the body's response.

E) B) and D)
F) None of the above

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Where are the peripheral chemoreceptors located? 1) In the arch of the aorta 2) In the bifurcations of carotid arteries 3) On the ventrolateral surfaces of the medulla


A) 1 and 2 only
B) 2 only
C) 2 and 3 only
D) 1 and 3 only

E) All of the above
F) C) and D)

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A

While observing a patient's breathing, you note that the depth and rate first increase, then decrease, followed by a period of apnea. Which of the following terms would you use in charting this observation?


A) Apneustic breathing
B) Biot's breathing
C) Cheyne-Stokes breathing
D) Paradoxical breathing

E) B) and D)
F) A) and B)

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What has the primary responsibility for sensing and responding to changes in blood levels of CO2?


A) Apneustic centers
B) Central chemoreceptors
C) Peripheral chemoreceptors
D) Pneumotaxic center

E) B) and D)
F) C) and D)

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In patients with closed-head injuries, what may happen in the presence of hypercapnia?


A) High CO2 increases the risk of psychotic events.
B) High CO2 levels cause cerebral vasodilation and improved oxygenation.
C) Severe cerebral vasoconstriction results in anoxia and stroke.
D) Vasodilation causes increased intracranial pressure and possibly stops blood flow.

E) B) and C)
F) C) and D)

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What happens in chronic hypercapnia? 1) The central chemoreceptive response to CO2 is decreased. 2) The cerebrospinal fluid pH is restored to normal. 3) Responsiveness to increased CO2 is decreased.


A) 1 only
B) 1 and 2 only
C) 2 and 3 only
D) 1, 2, and 3

E) B) and C)
F) None of the above

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What does apneustic breathing indicate?


A) Damage to the cerebrum
B) Damage to the pons
C) Spinal cord transaction
D) Vagal nerve damage

E) A) and B)
F) B) and C)

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Sensory input to the dorsal respiratory neurons from the lungs, airways, and peripheral chemoreceptors is provided via which nerves? 1) Glossopharyngeal 2) Phrenic 3) Vagus 4) Trigeminal


A) 1 and 2 only
B) 1, 2, and 4 only
C) 1 and 3 only
D) 2 and 3 only

E) A) and C)
F) C) and D)

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